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Biologic Applications

The application of the Bio-Logic SFM family of instruments is large and evolving. We have made our instruments as versatile as possible so that they are not the limiting factor in your research.

Here is a sample of how our instruments have been used:

Stopped-Flow Experiments

  • Protein Folding
  • Conformational Changes
  • Substrate Binding
  • Enzyme Kinetics
  • Substrate Transport in Vesicles

Measured by

  • UV/VIS Absorbance
  • Light Scattering
  • Fluorescence
  • Circular Dichroism
  • Fluorescence Anisotropy
  • FTIR
  • X-ray scattering
  • Conductivity
  • Mass Spectrometry

Quench-Flow Experiments

  • Substrate Binding
  • Enzyme Kinetics
  • Protein Folding Kinetics
  • Conformational Changes
  • Second Messenger Studies

Measured by

  • UV/VIS Absorbance
  • Light Scattering
  • Fluorescence
  • Circular Dichroism
  • Fluorescence Anisotropy
  • FTIR
  • X-ray scattering
  • Conductivity
  • Mass Spectrometry

Freeze Quench Methods

  • Trapping of kinetic intermediates by ultra-fast freezing

Measured by

  • olid-State NMR
  • EPR
  • X-ray scattering
  • EXASF
     
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