Rapid Kinetics Instrumentation

Since 1983, Bio-Logic has been developing and manufacturing stopped-flow and quench-flow instruments of superior performance, extreme versatility and highest reliability. With dead times of as low as 0.25 ms Bio-Logic stopped-flow spectrometers are the fastest of its kind on the actual market.

Several technological key features make Bio-Logic's mixing devices to one of the finest research instruments in the field:

• Driving mechanism: All Bio-Logic stopped-flow and quench-flow mixers are equipped with separate stepping motor drives, one for each syringe. This innovative drive technique allows to exactly control the volume injected by each syringe and the total flow rate, thus helping to work as economic as possible with precious sample. It gives direct automatic access to intermediate aging (sequential mixing) and concentration-dependent studies (in case of three or more syringes); syringes can be (re)filled at any height independently from each other.
• Mixer-Design: All Bio-Logic SFM models are equipped with the proved Ball-Mixer design that assures complete and efficient mixing in the most stringent conditions: wide range of flow rates from 1 to 18 ml/s, wide range of mixing ratios from 1:1 to 1:100, mixing of two solutions with extreme differences in density and viscosity (e.g; high sugar concentrations versus water).
• Hardstop-technology: SFM instruments from Bio-Logic use a sophisticated synchronization between the stop of stepping motors and the closure of an electromagnetic valve (hard stop) to efficiently stop the flow. Creation of over-pressure can be avoided as much as possible even at very high flow rates. Therefore, pressure sensitive samples can be protected from damage and possible arte-factual results avoided.
• Modularity: The completely modular design of Bio-Logic's instrumentation allows to combine the mixer of choice (two, three or four syringes) with the most suitable spectrometer system. Therefore a rapid kinetics platform can be composed to the dedicated needs for a particular research. Such a system stays also open for further interesting upgrades should the research field evolve in the future: chemical quench-flow, automated titration, freeze-quench, optical delay and optical quench, adaptation to user's own detection systems, etc.